Clorpactin WCS-90 is a stabilized organic derivative of hypochlorous acid. It is a white, water soluble powder. It has high antimicrobial activity that is markedly cidal rather than inhibitory. In concentrations ranging from 0.2-0.5%, its solutions destroy microorganisms by oxidation and hypochlorination, regardless of their type or resistance to other agents. Exposing microbes to a solution of Clorpactin WCS-90 results in microbial lysing and destruction. There have been no reported cases of adverse effects on healthy tissue despite this powerful activity.

Clorpactin WCS-90 has many medical uses, including cleansing of the bowel prior to colon resection.¹ Intraoperative colonic irrigation with an antiseptic has been shown to be an effective method of wound sepsis prevention.² Clorpactin WCS-90 has been shown to be an effective intestinal antiseptic.^{3, 4, 5} Its solutions exhibit pronounced wetting properties, which assist in dissolving stool, and liberate hypochlorous acid in vapor form, which is lethal to microorganisms even beyond the reach of the solution. Its broad antimicrobial spectrum, lack of allergenicity, clean pleasant odor, lubricating texture, clear transparent color, and lack of toxicity to healthy mucosa, make it an excellent choice for irrigation during routine colon and anorectal surgery.

Clinical and experimental studies provide evidence that perioperative implantation of viable shed cancer cells is a cause for local cancer recurrence. ^{6, 7, 8, 9, 10, 11, 12} Hypochlorite solutions have been shown to be effective tumoricidal agents. ^{3, 13, 14} In experimental models, irrigations of the colon lumen with sodium hypochlorite and other tumoricidal agents prior to anastomosis produced significant decreases in cancer cell implantation rates. ^{15, 16, 17} In order to prevent local cancer recurrence, rectal irrigation with and without tumoricidal agents has been widely practiced, ^{18, 19} although the efficacy of this procedure remains unproven. ²⁰ Clorpactin and other hypochlorite solutions are among the tumoricidal agents that have been used clinically for this purpose. ^{21, 22}

When used as recommended, Clorpactin WCS-90 is safe and well-tolerated. Many millions of liters of solution have been used since 1955 with no reports of toxicity or allergic reaction, despite the variety of conditions treated and methods of application.

Based on many years of clinical use and data from numerous clinical and experimental studies, Clorpactin WCS-90 has been shown to have numerous advantages as a topical chemotherapeutic agent: